Long-term effects of preterm birth on cortical folding trajectories in early childhood
Yong Hun Jang, Jong Min Kim, Bong Gun Lee, Jeong-Kyu Hoh, Gang Yi Lee, Hyun Ho Kim, Ilwoo Lyu, Hyun Ju Lee · 2026
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Description
Yong Hun Jang and co-authors follow the folds of the brain in children born too early. Cortical folding begins before birth and reorganizes fast in early childhood, so a preterm start might bend the whole trajectory. Their 2026 paper analyzes brain scans from 56 preterm children and 206 full-term peers, all aged one to seven, measuring how deeply and tightly each region of cortex is folded.
Preterm children showed a regional pattern: shallower, simpler folding in both superior temporal gyri and the left superior frontal gyrus, plus simplified folds in cingulate regions at the brain's midline. In the temporal cortex, fold depth related to developmental outcomes differently in the two groups. The authors argue these folding signatures, readable from ordinary scans, could help flag which preterm children carry traces of their early start and might benefit most from support.
Catalog record
| CREATOR | Yong Hun Jang, Jong Min Kim, Bong Gun Lee, Jeong-Kyu Hoh, Gang Yi Lee, Hyun Ho Kim, Ilwoo Lyu, Hyun Ju Lee |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |