The Role of Macrophages in Acute Pancreatitis: From Inflammatory Drivers to Therapeutic Targets
Zhihong Xu, Yi-Chen Sui, Li-Ping Sheng · 2026
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Description
Zhihong Xu, Yi-Chen Sui, and Li-Ping Sheng review in a 2026 article the double life of macrophages in acute pancreatitis, first fanning the inflammation and later helping to end it. These immune cells act in the pancreas and far beyond it, in fat, liver, lung, and spleen. Early on they take the inflammatory form and amplify the attack.
As the disease turns, they switch to a repair form that promotes resolution. Tuning that switch, and the cells' self-eating cleanup, is the therapeutic hope. The review maps what is known and what is missing, including how these cells talk to the pancreas's own enzyme cells.
Catalog record
| CREATOR | Zhihong Xu, Yi-Chen Sui, Li-Ping Sheng |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 21 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |