Recurrent Autoimmune Encephalitis in a Patient With Autoimmune Polyendocrine Syndrome Type 1

Jason T Stemple, Kamal Abulebda, Grace F Ryan, Nadine G Haddad, Alden F Dewey, Jennah C Foltz, Laurence E Walsh, Riad Lutfi, Lipi Buch · 2026

Read Recurrent Autoimmune Encephalitis in a Patient With Autoimmune Polyendocrine Syndrome Type 1 by Jason T Stemple, Kamal Abulebda, Grace F Ryan, Nadine G Haddad, Alden F Dewey, Jennah C Foltz, Laurence E Walsh, Riad Lutfi, Lipi Buch (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13181320.txt.

Description

A medical team reports a rare case of brain inflammation returning in a teenager with a broad immune disorder, in a 2026 case report. The girl has autoimmune polyendocrine syndrome type 1, a single-gene condition where the immune system attacks the body's own glands. She had suffered autoimmune encephalitis before and arrived gravely ill with confusion and seizures.

Brain scans showed injury spots in the corpus callosum, and electrical tests showed near-constant seizure activity. High levels of one antibody, GAD65, supported a relapse once other causes were ruled out. Strong immune treatment, including plasma exchange, steroids, and rituximab, brought marked improvement. The authors say the case is the first reported instance of the brain condition returning in this syndrome. Early, forceful immune therapy made the difference, they argue.

Catalog record

CREATORJason T Stemple, Kamal Abulebda, Grace F Ryan, Nadine G Haddad, Alden F Dewey, Jennah C Foltz, Laurence E Walsh, Riad Lutfi, Lipi Buch
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE16 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13181320

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