Protective effects auraptene alone and in combination with estradiol on intestine injury induced by traumatic brain injury in male rats: The role of oxidative stress
Sedigheh Amiresmaili, Azadeh Seyedjoodaki, Ahmad Vosughi Motlagh, Amir Reza Afshari, Fatemeh Maghool, Zakieh Keshavarzi · 2026
Read Protective effects auraptene alone and in combination with estradiol on intestine injury induced by traumatic brain injury in male rats: The role of oxidative stress by Sedigheh Amiresmaili, Azadeh Seyedjoodaki, Ahmad Vosughi Motlagh, Amir Reza Afshari, Fatemeh Maghool, Zakieh Keshavarzi (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13180244.txt.
Description
Sedigheh Amiresmaili and co-authors test a citrus compound against gut injury after brain trauma in a rat study from 2026. Traumatic brain injury often wounds the intestine too, through stress and oxidation. Auraptene, a natural compound from citrus peel, fights oxidation. Estradiol, a hormone, may add protection.
Twelve groups of male rats separated the effects. Three doses of auraptene, estradiol alone, and all pairings were tried. Treatment ran five days before the injury for auraptene groups. The top dose, alone and paired, cut brain water content notably. Intestine measures were scored beside brain ones. Natural compounds shielding the gut-brain axis could soften a hidden half of head injury care.
Catalog record
| CREATOR | Sedigheh Amiresmaili, Azadeh Seyedjoodaki, Ahmad Vosughi Motlagh, Amir Reza Afshari, Fatemeh Maghool, Zakieh Keshavarzi |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 28 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |