Ginsenosides in the management of depression: a comprehensive pharmacological review

Min Ren, Xin Tao, Hong Chang, Hui-Chang Bi, Simon Ming-Yuen Lee, Jian-Bo Wan · 2026

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Description

Min Ren and co-authors wrote a 2026 review of ginseng compounds as a possible aid for depression. Depression is common, often comes with other long-term illness, and current drugs help only in part and can cause side effects. Ginsenosides are the main active compounds in Panax ginseng, a herb long used in East Asia.

The review gathers lab and early clinical work on how these compounds act. They seem to tune brain signal chemicals, calm the stress hormone system, and help new nerve cells grow. They may also ease brain swelling, cell stress, and gut microbe imbalance. Rare forms with fewer sugar parts may enter the body better. The authors weigh targets and gaps before wider clinical use.

Catalog record

CREATORMin Ren, Xin Tao, Hong Chang, Hui-Chang Bi, Simon Ming-Yuen Lee, Jian-Bo Wan
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE111 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13179617

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