Sequential Use of Systemic Therapy With Locoregional Therapy for Hepatocellular Carcinoma in Japan: Analyses of Real‐World Data Based on a Health Claims Database
Junichi Shindoh, Sachiyo Shirakawa, Ikumi Takashima, Daisuke Kawai, Kenichiro Nishida, Hiroshi Kitagawa · 2026
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Description
Junichi Shindoh and five co-authors mapped how liver cancer is treated in Japan, in a 2026 study of health claims. Care there leans on local treatments aimed at the tumor, such as surgery or heat. New whole-body drugs have since joined the field, and how the two are sequenced was unclear.
Claims for more than fifteen thousand patients from 2020 to 2022 were traced from their first local treatment. Few had whole-body drugs before that step, and few had upkeep drugs after it. The need for a next treatment within six months varied a lot by first treatment type. The authors say local care alone stayed the norm, and call for a clear shared plan for mixing the two.
Catalog record
| CREATOR | Junichi Shindoh, Sachiyo Shirakawa, Ikumi Takashima, Daisuke Kawai, Kenichiro Nishida, Hiroshi Kitagawa |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |