Frequency of mixed neuropathologies in individuals with Down syndrome with and without Alzheimer's dementia
Lisi Flores-Aguilar, Thomas D Zaikos, Isabel Rivera, Sierra T Wright, Jerry Lou, Brianna Gawronski, Lourdes Gonzalez, Jillian V Berry, Jeremy Rouanet, Natalie C Edwards, Dan K Hoang, Kevin Wood, Ann-Charlotte Granholm, Elliott J Mufson, Edwin S Monuki, Milos D Ikonomovic, Julia Kofler, Eric W Doran, · 2026
Read Frequency of mixed neuropathologies in individuals with Down syndrome with and without Alzheimer's dementia by Lisi Flores-Aguilar, Thomas D Zaikos, Isabel Rivera, Sierra T Wright, Jerry Lou, Brianna Gawronski, Lourdes Gonzalez, Jillian V Berry, Jeremy Rouanet, Natalie C Edwards, Dan K Hoang, Kevin Wood, Ann-Charlotte Granholm, Elliott J Mufson, Edwin S Monuki, Milos D Ikonomovic, Julia Kofler, Eric W Doran, (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13179220.txt.
Description
Lisi Flores-Aguilar and co-authors count mixed brain pathologies in Down syndrome in 2026. People with Down syndrome develop Alzheimer type brain change by about age forty. Most face dementia by their early fifties. How often other brain diseases mix in was not well mapped.
The team examined brains from adults who were tracked in life and after death. They scored Alzheimer change plus vessel amyloid, Lewy bodies, and other common age linked changes. Scarring of a key memory area was also checked. Knowing the full mix can refine how doctors read scans and plan care for this group.
Catalog record
| CREATOR | Lisi Flores-Aguilar, Thomas D Zaikos, Isabel Rivera, Sierra T Wright, Jerry Lou, Brianna Gawronski, Lourdes Gonzalez, Jillian V Berry, Jeremy Rouanet, Natalie C Edwards, Dan K Hoang, Kevin Wood, Ann-Charlotte Granholm, Elliott J Mufson, Edwin S Monuki, Milos D Ikonomovic, Julia Kofler, Eric W Doran, |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 78 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |