Molecular and therapeutic frontiers in anemia therapy
Nilesh Rai, Omar Abdel-Wahab, Lingbo Zhang · 2026
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Description
Nilesh Rai and co-authors survey the frontiers of anemia treatment, from genes to new drugs. Anemia touches a third of the world's people and stems from failed red blood cell production. Decades of work have mapped its molecular causes, yet turning that map into targeted cures has proved slow.
Proven paths include tuning the signals that erythropoietin drives and guarding the body's iron balance with small molecules and oral supplements. Newer work targets control genes and splicing proteins inside young red cells, and crafts drugs for single mutations. Fresh evidence even ties nerve signals and mitochondrial shape to blood making. The review weighs these routes and the problem of drug resistance along the way.
Catalog record
| CREATOR | Nilesh Rai, Omar Abdel-Wahab, Lingbo Zhang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |