Efficacy and safety evaluation of artificial intelligence-identified antimicrobial peptides targeting avian pathogenic Escherichia coli in broiler chickens
Emre Demirsoy, Teagan I Parkin, Shaeleen E Mihalynuk, Anna H Dema, Lorissa Corrie, Marika E Heilker, Haley N Kuecks-Winger, Anat Yanai, Uluc B Birol, Michael McIlwee, Kay de Wet, Mathijs Knipscheer, Victoria Bowes, Vanessa Tuytel, Liam Ritchie, Wolfgang Köster, Emil Berberov, William R Cox, Monica K · 2026
Read Efficacy and safety evaluation of artificial intelligence-identified antimicrobial peptides targeting avian pathogenic Escherichia coli in broiler chickens by Emre Demirsoy, Teagan I Parkin, Shaeleen E Mihalynuk, Anna H Dema, Lorissa Corrie, Marika E Heilker, Haley N Kuecks-Winger, Anat Yanai, Uluc B Birol, Michael McIlwee, Kay de Wet, Mathijs Knipscheer, Victoria Bowes, Vanessa Tuytel, Liam Ritchie, Wolfgang Köster, Emil Berberov, William R Cox, Monica K (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13177867.txt.
Description
Emre Demirsoy and co-authors test AI-found germ-killing peptides as a stand-in for antibiotics in broiler chickens, in a study from 2026. Heavy antibiotic use in farming breeds resistant bacteria, which drives the hunt for new options. Peptides are short protein chains that can kill germs and calm immune overreaction. A machine learning screen had picked candidates from hundreds of options.
Three lead peptides went into egg and pen trials. Infected chicks given one peptide showed fewer germ-positive organs and gained far more weight. In farm-scale pens, two peptides raised survival rates by day thirty-five. Growth and feed use stayed normal across the trials. One peptide also tamed a fierce immune signal in lab cells. The authors call the pair promising for poultry use.
Catalog record
| CREATOR | Emre Demirsoy, Teagan I Parkin, Shaeleen E Mihalynuk, Anna H Dema, Lorissa Corrie, Marika E Heilker, Haley N Kuecks-Winger, Anat Yanai, Uluc B Birol, Michael McIlwee, Kay de Wet, Mathijs Knipscheer, Victoria Bowes, Vanessa Tuytel, Liam Ritchie, Wolfgang Köster, Emil Berberov, William R Cox, Monica K |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 68 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |