How I Treat: Immune dysregulation in Down syndrome

Melissa Gans, Matthew Wyke, Kayra Somay, Willa Thorson, Dusan Bogunovic · 2026

Read How I Treat: Immune dysregulation in Down syndrome by Melissa Gans, Matthew Wyke, Kayra Somay, Willa Thorson, Dusan Bogunovic (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13177381.txt.

Description

Gans and co-authors explain how they treat immune problems in Down syndrome in this 2026 clinical article. Immune dysregulation in Down syndrome is common yet often missed. Infection is the leading cause of death in this group.

The authors describe a mix of weak immune defense, body anatomy, and overactive inflammation. Patients also face many autoimmune and inflammatory diseases across skin, brain, and metabolism, which can resist standard immune-calming drugs. The article teaches through real cases from the authors' own clinic. Each vignette shows how they work through diagnosis and treatment choices. The piece is a practical guide for clinicians who care for people with Down syndrome.

Catalog record

CREATORMelissa Gans, Matthew Wyke, Kayra Somay, Willa Thorson, Dusan Bogunovic
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE42 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13177381

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