Metal‐Free, Chemoselective Reduction of Aromatic Nitro Compounds in Water at Room Temperature

Maria Batzaki, Thomas S. A. Heugebaert, Christian V. Stevens · 2026

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Description

Batzaki, Heugebaert, and Stevens report a metal free way to reduce aromatic nitro compounds in twenty twenty-six. The reaction turns nitro groups into amines, a key step in making many chemicals. Their method uses tetrahydroxydiboron as the reducing agent and a bipyridine organocatalyst. Water serves as the solvent at room temperature. The process is rapid and selective, sparing other sensitive groups on the molecule. Yields were good to excellent across the tested compounds. The authors present it as a mild, greener route to aromatic amines.

Catalog record

CREATORMaria Batzaki, Thomas S. A. Heugebaert, Christian V. Stevens
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE44 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13176622

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