Transcriptomic profiling reveals substrate- and shear stress-dependent maturation of human small intestinal epithelial cells
Nadra Alzain, Ahed Almalla, Ketaki Sandu, Lorenz Gerbeth, Jörn F. Ziegler, Catharina Gutwein, Patrick Weidner, Rainer Glauben, Marie Weinhart, Britta Siegmund · 2026
Read Transcriptomic profiling reveals substrate- and shear stress-dependent maturation of human small intestinal epithelial cells by Nadra Alzain, Ahed Almalla, Ketaki Sandu, Lorenz Gerbeth, Jörn F. Ziegler, Catharina Gutwein, Patrick Weidner, Rainer Glauben, Marie Weinhart, Britta Siegmund (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13175875.txt.
Description
Nadra Alzain and co-authors grow human gut lining cells on printed gels that copy real gut tissue, to see which cues help the cells grow up, in a study from 2026. Gut cells grown in dish soon lose their form and use unless the dish feels like home. The gels, made from pig gut sheet, sat in a flow rig that could rub the cells with a soft stream.
Gene reads show the gel beat plain coated plastic on cell life and growth up paths. Cells on gel kept steadier gene marks over time and leaned more toward the soak up cell kind. Flow then fired up fuel and guard paths and pushed the same lean. The rig gives labs a home like gut model for drug and growth tests.
Catalog record
| CREATOR | Nadra Alzain, Ahed Almalla, Ketaki Sandu, Lorenz Gerbeth, Jörn F. Ziegler, Catharina Gutwein, Patrick Weidner, Rainer Glauben, Marie Weinhart, Britta Siegmund |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |