Retinal Pathology and Synucleinopathy in the Visual Pathway of α‐Synuclein Preformed Fibril Mouse Model of Parkinson's Disease
Qin Zhang, Xin‐Yi Qian, Tao Peng, Xiao‐Ou Hou, Zhen‐Yuan Ma, Jiang Huang, Li‐Fang Hu, Wei‐Feng Luo · 2026
Read Retinal Pathology and Synucleinopathy in the Visual Pathway of α‐Synuclein Preformed Fibril Mouse Model of Parkinson's Disease by Qin Zhang, Xin‐Yi Qian, Tao Peng, Xiao‐Ou Hou, Zhen‐Yuan Ma, Jiang Huang, Li‐Fang Hu, Wei‐Feng Luo (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13175198.txt.
Description
Qin Zhang and co-authors track how Parkinson's disease in mice first harms sight in a 2026 study. Male mice got a disease-protein seed shot into the brain, or a plain salt shot. Sight was tested at three and six months, and eye and brain tissue was read for protein clumps and cell marks.
By three months, seeded mice showed slower and weaker sight signals, and the gap grew by six months. Eye shape held, but clumps sat in eye nerve cells, with less of a key nerve chemical and more glial stir. Clumps also spread through sight and linked brain zones. Early eye harm may flag the disease ahead of shakes.
Catalog record
| CREATOR | Qin Zhang, Xin‐Yi Qian, Tao Peng, Xiao‐Ou Hou, Zhen‐Yuan Ma, Jiang Huang, Li‐Fang Hu, Wei‐Feng Luo |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 70 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |