A dating app for extracellular adhesion proteins
Casey D. Gailey, David M. Miller · 2026
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Description
Casey Gailey and David Miller wrote in 2026 about a genome-wide screen that maps how proteins on cell surfaces grip each other. Cells display dense crowds of such proteins, and their pairings steer growth, immunity, and nerve wiring. A team led by Nawrocka ran a biochemical screen in a tiny worm to catalog these pairings at full-genome scale.
The catalog turned up new players in nerve guidance, insulin signaling, growth factor action, and neuron links. Gailey and Miller playfully frame the screen as a dating app for proteins, since it tests who pairs with whom. The matches give biologists fresh leads on how cells talk.
Catalog record
| CREATOR | Casey D. Gailey, David M. Miller |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 10 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |