Jagged-1 mutation is associated with congenital heart defects: a case report
Othman Alahmed, Manal Alaamery, Fahad Alhabshan, Farah Chaikhouni, Mohamed S. Kabbani, Patrice Bouvagnet, Salam Massadeh · 2026
Read Jagged-1 mutation is associated with congenital heart defects: a case report by Othman Alahmed, Manal Alaamery, Fahad Alhabshan, Farah Chaikhouni, Mohamed S. Kabbani, Patrice Bouvagnet, Salam Massadeh (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13173698.txt.
Description
Othman Alahmed and six co-authors report a case linking a Jagged-1 gene mutation to congenital heart defects in a Saudi child. Such defects span mild to grave forms, and flaws in signal genes like JAG1 are one cause. The report came out in twenty twenty-six.
The girl was born extremely early and needed breathing support at once. She developed lung disease and high lung pressure. At eight months, heart scans showed a large hole between the upper chambers and an open duct. The duct was closed with success. She also grew poorly. The authors stress care shaped to each child's gene and body profile.
Catalog record
| CREATOR | Othman Alahmed, Manal Alaamery, Fahad Alhabshan, Farah Chaikhouni, Mohamed S. Kabbani, Patrice Bouvagnet, Salam Massadeh |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 20 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |