389 Fronto-parietal white matter integrity and neurometabolic profiles in medication-naïve first-episode psychosis
James Bryant, Tobias Goodwin-Allcock, Ravi Tripathi, Adrienne C. Lahti, Nina V. Kraguljac · 2026
Read 389 Fronto-parietal white matter integrity and neurometabolic profiles in medication-naïve first-episode psychosis by James Bryant, Tobias Goodwin-Allcock, Ravi Tripathi, Adrienne C. Lahti, Nina V. Kraguljac (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13173217.txt.
Description
James Bryant and co-authors study white matter in people with a first episode of psychosis who have taken no drugs yet. Their 2026 paper deals with a major tract that links the front and side parts of the brain. Past scans show lower order in that tract in psychosis. The chemical roots of that change are poorly known.
Scans of brain structure and chemistry were taken in forty eight patients and thirty nine healthy controls. Two chemicals differed between groups in both front and side white matter. Order in the tract also differed. When both chemicals were modeled together, each tied to tract order in a distinct area. The link between one chemical and tract order was stronger in patients than in controls. The authors probe how cell harm may drive the change.
Catalog record
| CREATOR | James Bryant, Tobias Goodwin-Allcock, Ravi Tripathi, Adrienne C. Lahti, Nina V. Kraguljac |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |