497 From hypertension to fibroids: Translating cardiovascular therapeutics for women’s health

Alvina Pan, Valentina Vanos, Mostafa Borahay · 2026

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Description

Alvina Pan, Valentina Vanos, and Mostafa Borahay test whether heart drugs can be reused to treat womb fibroids. Their 2026 study uses mice given human fibroid tissue and matched womb tissue. Fibroids are growths that are not cancer. They hit Black women at higher rates and are closely tied to heart and vessel disease. The drugs tested act on a hormone system that controls blood pressure.

Mice got one of two such drugs, the hormone itself, or a control. Growths were measured each week with a hand tool. Early data from all twenty four mice show varied growth, with no clear dose pattern. Lab tests on tissue will check cell growth, scarring, and immune cells. Those results may show effects that size alone does not.

Catalog record

CREATORAlvina Pan, Valentina Vanos, Mostafa Borahay
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE2 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13172988

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