Editorial: Viral surface spikes: host cell entry, immune responses and evasion, and implications for viral infection, inhibition and rebound
Sophie M.-C. Gobeil, Maolin Lu, Amit Sharma · 2026
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Description
Sophie Gobeil, Maolin Lu, and Amit Sharma opened a journal collection in 2026 on the spike proteins that viruses use to enter cells. Spikes on flu, HIV, and the COVID virus both unlock the cell door and draw the immune system's fire, making them prime targets for vaccines and drugs.
The editorial explains how spikes also hide: sugar coats, rapid mutation, and shape shifting help them dodge antibodies. That hiding drives drug resistance and rebound infections. The collection gathers three reviews and eight research papers on spike structure, entry, and immune escape. The editors argue that detailed spike knowledge is the surest route to blocking infection at the door.
Catalog record
| CREATOR | Sophie M.-C. Gobeil, Maolin Lu, Amit Sharma |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 7 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |