POEMS syndrome with multiple ganglioside/paraneoplastic antibodies misdiagnosed as CIDP: a case report
Mengmeng Fan, Jiaxiu He, Shihui Sun, Linyuan He, Zhao Zhong · 2026
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Description
Mengmeng Fan and four co-authors untangle a misdiagnosis in a 2026 case report. A patient arrived with tingling and numbness in the legs, a picture that looked like a common inflammatory nerve disease. The label stuck at first, as it often does: the rare condition hiding underneath shares the same early nerve symptoms.
The true diagnosis was POEMS syndrome, a multisystem disorder driven by abnormal plasma cells and a growth factor gone high. Its name lists its parts: nerve damage, enlarged organs, hormone problems, an abnormal blood protein, and skin changes. Careful lab work and tissue analysis separated it from the inflammatory look-alike. The authors pair the case with a literature review to sharpen the distinction. Their warning is practical: when a supposed inflammatory neuropathy behaves oddly or resists treatment, hunt for the systemic clues before the wrong treatment wastes time.
Catalog record
| CREATOR | Mengmeng Fan, Jiaxiu He, Shihui Sun, Linyuan He, Zhao Zhong |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |