SLC2A3 Expression is Differentially Associated with Postoperative Recurrence, Complications, and Liver Metastasis in Colorectal Cancer
Su Peng, Juan Zuo, Zhangyi Wang, Kang Zheng, Feng Lu · 2026
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Description
Su Peng, Juan Zuo, Zhangyi Wang, Kang Zheng, and Feng Lu study a sugar-transport gene in bowel cancer in a 2026 paper. The gene, SLC2A3, helps cells pull in glucose, and hungry tumors often raise it. The team asked whether its level in a tumor predicts spread to the liver, return of the cancer after surgery, or other complications.
Records and tissue from one hundred fifty surgical patients were analyzed. The gene's message ran far higher in tumors than in nearby healthy tissue. High levels tracked with liver spread, recurrence, and complications after surgery. In adjusted models, the links to recurrence and complications stood on their own. The link to liver spread faded once tumor grade was counted, hinting it works through that path. The authors propose the gene as a marker for sorting risk after surgery, with caution.
Catalog record
| CREATOR | Su Peng, Juan Zuo, Zhangyi Wang, Kang Zheng, Feng Lu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 60 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |