Efficacy and Safety of Oliceridine for Patient-Controlled Intravenous Analgesia in Elderly Patients Undergoing Laparoscopic Radical Resection Surgery for Gastrointestinal Malignant Tumors: A Prospective Randomized Controlled Non-Inferiority Clinical Trial
Jiameng Wang, Yue Shang, Chenyang Wang, Dongdong Zhang, Han Li, Qian Yu, Lei Tao, Li Sun, Changjun Gao · 2026
Read Efficacy and Safety of Oliceridine for Patient-Controlled Intravenous Analgesia in Elderly Patients Undergoing Laparoscopic Radical Resection Surgery for Gastrointestinal Malignant Tumors: A Prospective Randomized Controlled Non-Inferiority Clinical Trial by Jiameng Wang, Yue Shang, Chenyang Wang, Dongdong Zhang, Han Li, Qian Yu, Lei Tao, Li Sun, Changjun Gao (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13165471.txt.
Description
Jiameng Wang and eight co-authors test a newer opioid for self dosed pain care after gut cancer surgery in a 2026 trial. Older patients on standard pumps suffer many opioid side effects. Oliceridine, a biased opioid that leans on the pain path over the side effect path, may ease pain as well with less harm. The trial set it head to head against sufentanil.
Ninety elders set for scope surgery on gut tumors were split evenly between the two pumps for two days. Eighty eight were read. Total rest pain over the span came out near even, about seventy three points on the summed scale in both arms, inside the preset fairness margin. Side effect counts fill out the safety read. The authors call the new drug a fair match.
Catalog record
| CREATOR | Jiameng Wang, Yue Shang, Chenyang Wang, Dongdong Zhang, Han Li, Qian Yu, Lei Tao, Li Sun, Changjun Gao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 45 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |