Vasorelaxing Effect of Hydrolyzed Collagen from Salmon Skin in the Thoracic Aorta and Underlying Mechanisms
Pimchanok Mungmuang, Amnart Onsa-Ard, Jiraporn Tocharus, Rattapong Sungnoon, Rungusa Pantan, Krisana Nilsuwan, Soottawat Benjakul, Chainarong Tocharus · 2026
Read Vasorelaxing Effect of Hydrolyzed Collagen from Salmon Skin in the Thoracic Aorta and Underlying Mechanisms by Pimchanok Mungmuang, Amnart Onsa-Ard, Jiraporn Tocharus, Rattapong Sungnoon, Rungusa Pantan, Krisana Nilsuwan, Soottawat Benjakul, Chainarong Tocharus (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13163282.txt.
Description
Pimchanok Mungmuang and seven co-authors test whether salmon skin collagen relaxes blood vessels, in a 2026 study. The hydrolyzed collagen, a soup of small peptides from fish waste, is sold as a supplement, and its vascular effects were unmapped.
Rat aorta rings in organ baths tightened under standard drugs, then loosened when the collagen was added. The effect held without the vessel's inner lining, pointing at the muscle itself. Blocking one potassium channel blunted it; other channel blockers did not. A receptor blocker for adrenaline-like signals also cut the effect. The collagen further resisted calcium-driven tightening in calcium-free fluid. The authors trace a muscle-level mechanism with several cooperating parts.
Catalog record
| CREATOR | Pimchanok Mungmuang, Amnart Onsa-Ard, Jiraporn Tocharus, Rattapong Sungnoon, Rungusa Pantan, Krisana Nilsuwan, Soottawat Benjakul, Chainarong Tocharus |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 23 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |