Molecular Insights into Oral Manifestations in Sjögren’s Disease
Konstantina Xanthopoulou, Anna Siatra, Konstantinos I. Tosios, Eleni-Marina Kalogirou · 2026
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Description
Konstantina Xanthopoulou and co-authors review the molecular roots of mouth trouble in Sjögren disease. Their 2026 review deals with an autoimmune illness that attacks the glands that make spit and tears. Dry mouth is its hallmark, with damage that goes far past discomfort.
The review links mouth signs to the steps that drive the disease. Alarm signals in gland cells switch on interferon paths, which call in swelling signals. Cell death programs, faulty power plants in cells, and broken seals between cells then wreck the gland's work. The amount and mix of spit change as well. The authors map these chains to guide future care research on dry mouth in this disease.
Catalog record
| CREATOR | Konstantina Xanthopoulou, Anna Siatra, Konstantinos I. Tosios, Eleni-Marina Kalogirou |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 70 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |