The Impact of Alternate-Day Fasting on the Salivary Gland Ductal Compartments and the Differentiation Potential of Keratin 5+ Salivary Gland Progenitor Cells in an Induced Mouse Model of Sjögren’s-like Hyposalivation
Dongfang Li, Shoko Onodera, Qing Yu, Jing Zhou · 2026
Read The Impact of Alternate-Day Fasting on the Salivary Gland Ductal Compartments and the Differentiation Potential of Keratin 5+ Salivary Gland Progenitor Cells in an Induced Mouse Model of Sjögren’s-like Hyposalivation by Dongfang Li, Shoko Onodera, Qing Yu, Jing Zhou (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13163249.txt.
Description
Dongfang Li and three co-authors test whether alternate-day fasting helps dry-mouth disease in mice. Their 2026 study models Sjögren's-like low saliva flow, an immune attack on saliva glands. Fasting on alternate days had helped in the team's earlier model. Here they trigger the disease by immunizing special tracer mice with gland proteins.
Fasting eased the glands' low output in the induced model. Aging-cell markers fell, and a fiery alarm system in the glands quieted. The gains centered on the duct areas, where stem-like progenitor cells live. Stains showed a few of those marked cells turning toward fluid-making cell types. The work links fasting to healthier gland ducts and wider cell potential.
Catalog record
| CREATOR | Dongfang Li, Shoko Onodera, Qing Yu, Jing Zhou |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 24 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |