Molecular Characterization of Representative CPV-2c Isolates and Establishment of VP2-Targeted Nanobody-Based Immunodetection Tools
Liangkai Liu, Maohua Xia, Chengyao Hou, Danyu Chen, Chengyao Li, Xinggui Chen, Qinyuan Chu, Yue Sun, Shujun Liu, Yuqing Li, Hanlin Wang, Yan Zhu, Mengfang Yang, Hongning Wang, Caiwu Li, Xin Yang · 2026
Read Molecular Characterization of Representative CPV-2c Isolates and Establishment of VP2-Targeted Nanobody-Based Immunodetection Tools by Liangkai Liu, Maohua Xia, Chengyao Hou, Danyu Chen, Chengyao Li, Xinggui Chen, Qinyuan Chu, Yue Sun, Shujun Liu, Yuqing Li, Hanlin Wang, Yan Zhu, Mengfang Yang, Hongning Wang, Caiwu Li, Xin Yang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13163062.txt.
Description
Liangkai Liu and co-authors build detection tools for a dog virus in a 2026 study. Canine parvovirus still spreads despite vaccination, and one strain, CPV-2c, is rising in China and can threaten wildlife such as giant pandas. The team isolated a local strain in Sichuan and read its coat gene.
The strain matched a panda-derived virus exactly in that gene. From it they brewed tiny antibody-like binders, called nanobodies, aimed at the coat protein. A fused version detected the virus more sensitively in lab assays. Readers get standard reagents for tracking this virus in dogs and wildlife.
Catalog record
| CREATOR | Liangkai Liu, Maohua Xia, Chengyao Hou, Danyu Chen, Chengyao Li, Xinggui Chen, Qinyuan Chu, Yue Sun, Shujun Liu, Yuqing Li, Hanlin Wang, Yan Zhu, Mengfang Yang, Hongning Wang, Caiwu Li, Xin Yang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |