Establishment of Patient-Derived Organoids for Pediatric Cancer Research
Muhammad Younis, Tarlan Arjmandi, Mohammad Haque, Katherine McClain, Thussenthan Walter-Angelo, Franklin Back, Divya Gandra, Abigail Moore, Chandrika Behura, Vladimir S. Spiegelman, Hong-Gang Wang, Sinisa Dovat, Jeremy Hengst, Giselle Saulnier Sholler · 2026
Read Establishment of Patient-Derived Organoids for Pediatric Cancer Research by Muhammad Younis, Tarlan Arjmandi, Mohammad Haque, Katherine McClain, Thussenthan Walter-Angelo, Franklin Back, Divya Gandra, Abigail Moore, Chandrika Behura, Vladimir S. Spiegelman, Hong-Gang Wang, Sinisa Dovat, Jeremy Hengst, Giselle Saulnier Sholler (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13162899.txt.
Description
Muhammad Younis and co-authors give a step by step protocol for growing child cancer models in a 2026 paper. The models are organoids, small lab grown clusters that mimic a tumor. Child cancers differ from adult ones in how they arise. Good models of them have long been scarce.
The protocol starts with tumor samples from brain and solid cancers, plus marrow draws. It covers how to process the samples and feed the growing clusters. Steps for freezing the models for later use are included too. The team shows how to test the models with imaging and protein checks. Flow based cell sorting and tissue staining also feature. Shared methods like these can help labs compare results and hunt for new treatments.
Catalog record
| CREATOR | Muhammad Younis, Tarlan Arjmandi, Mohammad Haque, Katherine McClain, Thussenthan Walter-Angelo, Franklin Back, Divya Gandra, Abigail Moore, Chandrika Behura, Vladimir S. Spiegelman, Hong-Gang Wang, Sinisa Dovat, Jeremy Hengst, Giselle Saulnier Sholler |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |