Prospects of Chimeric Antigen Receptor T-Cell Therapy in Myelofibrosis: From Immunopathogenesis to Therapeutic Strategies
Lulu Kong, Chunling Fu, Lianggui Song, Wenxiao Wang, Mengchu Ji, Fei Li, Xiaofeng Shi, Wei Chen · 2026
Read Prospects of Chimeric Antigen Receptor T-Cell Therapy in Myelofibrosis: From Immunopathogenesis to Therapeutic Strategies by Lulu Kong, Chunling Fu, Lianggui Song, Wenxiao Wang, Mengchu Ji, Fei Li, Xiaofeng Shi, Wei Chen (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13162667.txt.
Description
Lulu Kong and co-authors review cell therapy prospects for a bone marrow disease in 2026. Myelofibrosis scars the marrow, enlarges the spleen, and drives body-wide inflammation. Current drugs ease symptoms but rarely clear the faulty clones or reverse scarring.
Engineered T cells have shown strong results in other blood cancers. The authors map targets on faulty cells and on the scarred niche around them. Hitting both could control clones and reshape the niche at once. Targets include surface markers, a scar protein, and signal paths that sustain the disease setting.
Catalog record
| CREATOR | Lulu Kong, Chunling Fu, Lianggui Song, Wenxiao Wang, Mengchu Ji, Fei Li, Xiaofeng Shi, Wei Chen |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 39 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |