Role of Cytokines in Bone Diseases and Their Therapeutic Application
Adrita Guha, Praneet Wahi, Girdhari Lal · 2026
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Description
Adrita Guha and co-authors review how cytokines, the immune system's signal proteins, shape bone health and disease, in a 2026 paper. Bone stays in balance through three cell types. Osteoclasts break bone down, osteoblasts build it up, and osteocytes sense strain and coordinate the other two. Immune signals can tip that balance.
The review covers both pro-inflammatory and calming cytokines. Each is traced through its effects on bone cell growth and work. Downstream effects on genes and metabolism also feature. Many bone diseases, from osteoporosis to arthritis damage, involve these signals. That makes cytokines tempting drug targets. The authors weigh which therapies look most promising. Clinicians gain a map from immune signals to bone care.
Catalog record
| CREATOR | Adrita Guha, Praneet Wahi, Girdhari Lal |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 79 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |