Cell Mechanics in Cancer: Integrating Mechanotransduction Pathways Within the Tumor Microenvironment
Merve Sevgi, Yağmur Işık, Caner Karaca, Esmahan Çağlar, Hasan Berkay Abdioğlu, Ferican Zendel, Yasemin Başbınar, Hüseyin Üvet · 2026
Read Cell Mechanics in Cancer: Integrating Mechanotransduction Pathways Within the Tumor Microenvironment by Merve Sevgi, Yağmur Işık, Caner Karaca, Esmahan Çağlar, Hasan Berkay Abdioğlu, Ferican Zendel, Yasemin Başbınar, Hüseyin Üvet (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13159791.txt.
Description
Merve Sevgi and co-authors review, in a 2026 paper, how the physical stiffness of cancer cells shapes tumor growth and spread. A cell's stiffness, springiness, and thickness steer how it moves, divides, and matures. In cancer, those traits shift markedly.
The review traces how the cell's internal scaffolding, its nucleus, and the surrounding matrix trade mechanical signals. Support cells within the tumor and the matrix recipe itself tune the mechanics further. Two signaling pathways that sense force receive close attention. These mechanical cues feed growth, invasion, and drug resistance. Reading cancer as a mechanical disease, not only a genetic one, opens fresh treatment angles.
Catalog record
| CREATOR | Merve Sevgi, Yağmur Işık, Caner Karaca, Esmahan Çağlar, Hasan Berkay Abdioğlu, Ferican Zendel, Yasemin Başbınar, Hüseyin Üvet |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 113 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |