The impact of previous history of malignant tumors/precancerous lesions on IVF/ICSI outcomes: a retrospective cohort study
Luyao Wang, Yifan Chu, Jiaxin Xie, Jiayun Chen, Yetan Liu, Shulin Yang, Peiwen Yang, Ying Xiao, Lei Jin, Ying Zhang, Jing Yue · 2026
Read The impact of previous history of malignant tumors/precancerous lesions on IVF/ICSI outcomes: a retrospective cohort study by Luyao Wang, Yifan Chu, Jiaxin Xie, Jiayun Chen, Yetan Liu, Shulin Yang, Peiwen Yang, Ying Xiao, Lei Jin, Ying Zhang, Jing Yue (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13159594.txt.
Description
Luyao Wang and ten colleagues asked whether a past cancer or precancer diagnosis worsens fertility treatment outcomes. Cancer incidence is rising in younger women, and many later seek IVF. The retrospective study ran at a Tongji Hospital reproductive center from twenty fifteen to twenty twenty-two. It enrolled 1,004 patients: 251 with a history of malignancy or precancerous lesions, matched against 753 controls. Cumulative live birth rate across cycles was the main outcome.
The history group showed significantly lower ovarian reserve and poorer embryo outcomes. Both conservative and optimistic cumulative live birth rates ran lower than in controls. Propensity matching balanced the groups' baselines before comparison. The twenty twenty-six findings help counselors give cancer survivors honest odds, and may influence how much time clinicians spend optimizing treatment before starting.
Catalog record
| CREATOR | Luyao Wang, Yifan Chu, Jiaxin Xie, Jiayun Chen, Yetan Liu, Shulin Yang, Peiwen Yang, Ying Xiao, Lei Jin, Ying Zhang, Jing Yue |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |