Thermal-enhanced self-heating microneedle patch for sustained progesterone delivery and improved pregnancy maintenance
Huiling Shen, Guifang Pan, Xingxing Li, Yichao Guo, Wenjian Zhang, Chenchen Wei, Hao Yuan, Jundong Shao · 2026
Read Thermal-enhanced self-heating microneedle patch for sustained progesterone delivery and improved pregnancy maintenance by Huiling Shen, Guifang Pan, Xingxing Li, Yichao Guo, Wenjian Zhang, Chenchen Wei, Hao Yuan, Jundong Shao (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13158400.txt.
Description
Huiling Shen and seven co-authors describe a 2026 patch that gives the hormone progesterone through the skin. Low levels of the hormone are a main cause of lost pregnancies. Shots given often are the usual fix, but they hurt, are a burden, and carry risks of their own.
The patch uses tiny needles loaded with the hormone and a backing that warms itself with a lime and charcoal mix. Heat sped drug release by more than seventy percent in tests. In pregnant rats, one patch held helpful levels for over ten hours. Pups survived more often and early births fell, with no outside device needed.
Catalog record
| CREATOR | Huiling Shen, Guifang Pan, Xingxing Li, Yichao Guo, Wenjian Zhang, Chenchen Wei, Hao Yuan, Jundong Shao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 60 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |