Mitochondrial RNA helicase DDX28 promotes cell cycle and DNA repair programs and shapes an immunosuppressive microenvironment in acute myeloid leukemia
Zi Wang, Yunli Liu, Xinzhu Guan, Miaoqing Ye, Xinxin Xu · 2026
Read Mitochondrial RNA helicase DDX28 promotes cell cycle and DNA repair programs and shapes an immunosuppressive microenvironment in acute myeloid leukemia by Zi Wang, Yunli Liu, Xinzhu Guan, Miaoqing Ye, Xinxin Xu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13158386.txt.
Description
Zi Wang and co-authors study a mitochondrial gene worker in a fast blood cancer in a 2026 analysis. The cancer relapses often, driven by tangles across cell power, growth pacing, DNA repair, and immune escape.
Across patient data sets, high levels of the worker track with worse survival and more blasts. Its high group shows gene programs for fast cycling and DNA repair, plus an immune scene rich in brake cells. Single cell reads place it in cancer blasts and worn out T cells. Muting it in lab cells slowed growth, movement, and invasion. The worker shapes up as both a mark and a lead.
Catalog record
| CREATOR | Zi Wang, Yunli Liu, Xinzhu Guan, Miaoqing Ye, Xinxin Xu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |