Metastatic Fibrolamellar Hepatocellular Carcinoma in a Young Adult: A Case Report and Narrative Review

Roy El Darzi, Christopher Ashy, Ali Khrayzat, Sally Chahine, Ayman Tawil, Sally Temraz · 2026

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Description

Roy El Darzi and co-authors report a rare liver cancer case in a young adult and review the literature in a 2026 paper. The cancer, fibrolamellar carcinoma, is a distinct subtype that arises in non scarred livers of adolescents and young adults, without viral hepatitis or chronic liver disease. It makes up under one percent of primary liver cancers and carries a characteristic gene fusion.

The patient came in with upper right abdominal pain and anemia, with preserved liver function. Imaging showed a large liver mass with a dead central area, and tissue tests fit the diagnosis, though fusion testing was not done. A combined drug plan was scheduled, but the patient declined fast before therapy could start.

Catalog record

CREATORRoy El Darzi, Christopher Ashy, Ali Khrayzat, Sally Chahine, Ayman Tawil, Sally Temraz
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE37 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13157843

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