Effects of Oliceridine versus Sufentanil on Postoperative Nausea and Vomiting in Patients Undergoing Modified Radical Mastectomy: A Double-Blind Randomized Controlled Trial
Lingyu Lu, Yan Zhou, Kaihang Xu, Zhenzhen Zhao, Lingling Ge, Yan Wang, Changli Wang, Rui Bao · 2026
Read Effects of Oliceridine versus Sufentanil on Postoperative Nausea and Vomiting in Patients Undergoing Modified Radical Mastectomy: A Double-Blind Randomized Controlled Trial by Lingyu Lu, Yan Zhou, Kaihang Xu, Zhenzhen Zhao, Lingling Ge, Yan Wang, Changli Wang, Rui Bao (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13157841.txt.
Description
Lingyu Lu and co-authors compare two pain drugs for the nausea that so often follows breast surgery. In a double-blind trial, 176 women having a modified radical mastectomy were randomized to anesthesia induction with either oliceridine, a newer opioid designed to spare side effects, or the standard sufentanil. Nausea and vomiting were tracked for 48 hours.
The newer drug cut the problem nearly in half: about 21 percent of its group felt sick against about 40 percent on the standard drug, with milder episodes too. Pain relief and the need for rescue doses matched between groups, and heart-related side effects were similar. The authors conclude the swap buys comfort without losing pain control.
Catalog record
| CREATOR | Lingyu Lu, Yan Zhou, Kaihang Xu, Zhenzhen Zhao, Lingling Ge, Yan Wang, Changli Wang, Rui Bao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |