Effectiveness of amoxicillin and amoxicillin-clavulanate for the treatment of community-acquired pneumonia in adults and children: a systematic review and meta-analysis

Lilia Potter-Schwartz, Myo MM Swe, Michael Sharland, Julia Anna Bielicki, Ben S Cooper, Cherry Lim · 2026

Read Effectiveness of amoxicillin and amoxicillin-clavulanate for the treatment of community-acquired pneumonia in adults and children: a systematic review and meta-analysis by Lilia Potter-Schwartz, Myo MM Swe, Michael Sharland, Julia Anna Bielicki, Ben S Cooper, Cherry Lim (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13157766.txt.

Description

Lilia Potter-Schwartz and co-authors weighed two common antibiotics for lung infection in this 2026 review. The drugs are amoxicillin and its partner form with clavulanate, both used for pneumonia caught outside hospitals. The team pooled trials in adults and children from four large databases.

Forty-four studies with about 45,400 patients went into the pool. Neither drug cured patients at a clearly higher rate than other antibiotics. Results for treatment failure were also too loose to rule out real gains or harms. A side analysis found no clear edge for the partner form over plain amoxicillin. The review leaves the choice between these drugs open and calls for sharper trials.

Catalog record

CREATORLilia Potter-Schwartz, Myo MM Swe, Michael Sharland, Julia Anna Bielicki, Ben S Cooper, Cherry Lim
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE27 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13157766

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