Attenuation of cue-induced heroin-seeking by the atypical antidepressant mirtazapine
Amanda L Persons, T Celeste Napier · 2026
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Description
Amanda Persons and Celeste Napier test a mood drug against heroin seeking in rats in a 2026 study. Opioid habit bends brain signals, among them two mood-linked ones the drug blocks in mixed ways. The same drug had cut meth seeking in rats, which raised the heroin ask.
Male rats learned to nose-poke for heroin shots over ten long days. After a rest day, cues tied to the drug were shown with no drug on tap, and seeking was scored. Dosed rats sought less when the cues came back. An old mood drug may blunt cue pull.
Catalog record
| CREATOR | Amanda L Persons, T Celeste Napier |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 18 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |