Protective role of calcitriol in PM2.5-induced apoptosis and inflammation in bronchial epithelial cells in vitro via vitamin D receptor-mediated Nrf2 signaling
Mutita Pluempreecha, Anyamanee Chatsirisupachai, Tanyapohn Soingam, Tasanee Onkoksoong, Tongchai Payungwong, Siwanon Jirawatnotai, Uraiwan Panich · 2026
Read Protective role of calcitriol in PM2.5-induced apoptosis and inflammation in bronchial epithelial cells in vitro via vitamin D receptor-mediated Nrf2 signaling by Mutita Pluempreecha, Anyamanee Chatsirisupachai, Tanyapohn Soingam, Tasanee Onkoksoong, Tongchai Payungwong, Siwanon Jirawatnotai, Uraiwan Panich (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13157050.txt.
Description
Mutita Pluempreecha and co-authors test whether calcitriol, the active form of vitamin D, can shield airway cells from fine dust harm, in a 2026 study. Fine particles from air pollution can stress lung cells, spark inflammation, and trigger cell death. The team treated human airway cells with calcitriol before exposing them to the particles.
Cells that got the treatment showed less cell death, less DNA damage, and lower inflammation signals. The treatment also raised levels of a protective receptor and boosted a pathway that switches on defense genes. Tests showed the receptor bound more strongly to the control sites of those genes. The findings suggest a way vitamin D may blunt pollution harm in the airways.
Catalog record
| CREATOR | Mutita Pluempreecha, Anyamanee Chatsirisupachai, Tanyapohn Soingam, Tasanee Onkoksoong, Tongchai Payungwong, Siwanon Jirawatnotai, Uraiwan Panich |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |