Lipid Analysis in Live Caenorhabditis elegans Using Solution-State NMR Spectroscopy
Florencia V. Guastaferri, Carla B. Delprato, Bruno Hernández Cravero, Gastón Prez, Diego De Mendoza, Andres Binolfi · 2026
Read Lipid Analysis in Live Caenorhabditis elegans Using Solution-State NMR Spectroscopy by Florencia V. Guastaferri, Carla B. Delprato, Bruno Hernández Cravero, Gastón Prez, Diego De Mendoza, Andres Binolfi (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13156696.txt.
Description
Florencia Guastaferri and five co-authors describe a protocol for reading fat composition in live roundworms using nuclear magnetic resonance. Fat balance shapes membranes, metabolism, and development, and its disruption links to many diseases. Standard fat analysis needs extraction, which kills the specimen and blocks live study.
By feeding worms labeled carbon, the team can resolve stored fats inside living animals with fine detail. The method separates normal worms from mutants with altered fat processing. A paired extract analysis catches membrane fats the live scan misses. The authors present the approach as a non destructive tool for small model organisms. It opens live views of whole body fat metabolism.
Catalog record
| CREATOR | Florencia V. Guastaferri, Carla B. Delprato, Bruno Hernández Cravero, Gastón Prez, Diego De Mendoza, Andres Binolfi |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 72 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |