Time Windows Used When Identifying Current Drug Use and Polypharmacy

Sabrina Giometto, Mette Reilev, Martin Thomsen Ernst, Henrik Støvring, Anton Pottegård · 2026

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Description

Sabrina Giometto and co-authors study how the look-back window chosen in drug registry research changes who counts as a current user, in a paper from 2026. Studies of drug use and of polypharmacy, taking many drugs at once, must draw a line in time. No agreement exists on where that line should sit.

Using Danish registries, the team varied the window and watched the exposure counts move. For daily long-term drugs, counts leveled off after about four to five months of look-back. For pain opioids the plateau came later, and for anti-inflammatory drugs it never came. In older adults, polypharmacy rates also swung with the definition used. Simulations tested how well each rule predicts true multi-drug use. The authors urge care, since the window alone can move a study's headline numbers.

Catalog record

CREATORSabrina Giometto, Mette Reilev, Martin Thomsen Ernst, Henrik Støvring, Anton Pottegård
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE18 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13156664

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