Multiscale Approximations to Understand the Complex Role of Microglia in Alzheimer's Disease
Patricia Martínez‐Tazo, Marina Mejias‐Ortega, Verónica López‐López, Aysha M. Bhojwani‐Cabrera, Emma Saxton, Santiago Canals, Giles Hardingham, Antonia Gutierrez, Jose P. Lopez‐Atalaya, Silvia De Santis · 2026
Read Multiscale Approximations to Understand the Complex Role of Microglia in Alzheimer's Disease by Patricia Martínez‐Tazo, Marina Mejias‐Ortega, Verónica López‐López, Aysha M. Bhojwani‐Cabrera, Emma Saxton, Santiago Canals, Giles Hardingham, Antonia Gutierrez, Jose P. Lopez‐Atalaya, Silvia De Santis (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13156479.txt.
Description
Patricia Martínez-Tazo and nine co-authors review the tangled roles of microglia, the brain's resident immune cells, in Alzheimer's disease, in this 2026 paper. These cells are no longer seen as one crew: their states shift with place in the brain, stage of disease, and genes. Findings now pour in from every scale, from DNA to brain scans to population data.
That flood has made the cells' part in the disease look double-edged and context-bound. The mini-review walks the scales in turn, molecular, cellular, and systemic. It ends with the open challenges to one shared, therapy-ready picture of microglia. The authors argue only stitched-together studies will settle when these cells help and when they harm.
Catalog record
| CREATOR | Patricia Martínez‐Tazo, Marina Mejias‐Ortega, Verónica López‐López, Aysha M. Bhojwani‐Cabrera, Emma Saxton, Santiago Canals, Giles Hardingham, Antonia Gutierrez, Jose P. Lopez‐Atalaya, Silvia De Santis |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 46 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |