Progressive White Matter Changes in Mitochondrial Disease: A Quantitative MRI Study
Nora Mickelsson, Jussi Hirvonen, Mika H. Martikainen · 2026
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Description
White matter harm growth in mitochondrial disease is charted by Nora Mickelsson, Jussi Hirvonen, and Mika Martikainen in work dated 2026. Such diseases strike the brain often, but the spread of white matter bright spots was poorly mapped. The team looked back at scans from thirty-six patients at one Finnish hospital. A cleared scan tool sized the spots and graded them as a share of head volume.
Spots sat in all top brain zones at first scan. Their size grew over time in most zones, chiefly near the core. Women and one gene group bore the heaviest loads. The growth outruns what blood vessel risk alone would explain.
Catalog record
| CREATOR | Nora Mickelsson, Jussi Hirvonen, Mika H. Martikainen |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 28 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |