Development of a hybrid tablet-integrated superporous hydrogel for gastro-retentive delivery of famotidine
Nilima Thombre, Kavita Chandramore, Anjali Tajanpure, Adel Al Fatease, Umme Hani, Ali H. Alamri, Mohammed Ghazwani, Roshan Jadhav, Meeta Ramaiya, Diya Anumone, Vedant Agrawal, Sharuk L. Khan, Fahadul Islam · 2026
Read Development of a hybrid tablet-integrated superporous hydrogel for gastro-retentive delivery of famotidine by Nilima Thombre, Kavita Chandramore, Anjali Tajanpure, Adel Al Fatease, Umme Hani, Ali H. Alamri, Mohammed Ghazwani, Roshan Jadhav, Meeta Ramaiya, Diya Anumone, Vedant Agrawal, Sharuk L. Khan, Fahadul Islam (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13155634.txt.
Description
Nilima Thombre and co-authors build a tablet that holds a stomach drug in place for longer release, in a study from 2026. The drug, famotidine, treats ulcers but is absorbed poorly and only in the upper gut. A system that lingers in the stomach could raise how much of each dose the body can use.
Their design joins a tablet with a very porous gel that swells fast. A foaming step makes the gel full of holes. The team varied two filler amounts in a set grid and graded each version for pore share, swelling, water uptake, shape, and drug content. Test results guided which mix best fits the goal of long stomach stay and slow, steady release.
Catalog record
| CREATOR | Nilima Thombre, Kavita Chandramore, Anjali Tajanpure, Adel Al Fatease, Umme Hani, Ali H. Alamri, Mohammed Ghazwani, Roshan Jadhav, Meeta Ramaiya, Diya Anumone, Vedant Agrawal, Sharuk L. Khan, Fahadul Islam |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 52 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |