Biogenesis and downstream effects of 3′,5′ and 2′,3′ cAMP isomers in plants
Mingyue Li, Monika Chodasiewicz, Malavika Muraleedharan, Israel M. Lopez, Michal Gorka, Olga Kerber, Saqer S. Alotaibi, Andrew D.L. Nelson, Rene Lenobel, Jaroslava Friedecká, Aleksandra Skirycz, Jiří Friml · 2026
Read Biogenesis and downstream effects of 3′,5′ and 2′,3′ cAMP isomers in plants by Mingyue Li, Monika Chodasiewicz, Malavika Muraleedharan, Israel M. Lopez, Michal Gorka, Olga Kerber, Saqer S. Alotaibi, Andrew D.L. Nelson, Rene Lenobel, Jaroslava Friedecká, Aleksandra Skirycz, Jiří Friml (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13155313.txt.
Description
Mingyue Li and co-authors show that plants run two parallel signaling systems on two forms of the same messenger, in a 2026 study. The messenger, cAMP, is famous in its 3',5' form. Its mirror twin, 2',3'-cAMP, was barely studied in plants. Lab assays showed plant enzymes of one kind make only the classic form from ATP. A protein domain of another kind makes the twin form from RNA instead.
Broad molecular profiling found the twins trigger largely distinct responses. The twin switches on wide stress-adaptation programs. The classic form fine-tunes nutrient balance and daily cell housekeeping. Some effects overlap, but the division of labor is clear. The authors say plants keep two separate cAMP channels, each with its own job in running physiology.
Catalog record
| CREATOR | Mingyue Li, Monika Chodasiewicz, Malavika Muraleedharan, Israel M. Lopez, Michal Gorka, Olga Kerber, Saqer S. Alotaibi, Andrew D.L. Nelson, Rene Lenobel, Jaroslava Friedecká, Aleksandra Skirycz, Jiří Friml |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 58 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |