NTRK Gene Fusions: A Compendium of Fusion Partners and Tumor Types
Soo-Ryum Yang, Matteo Repetto, Erin R. Rudzinski, Marilyn M. Li, Angshumoy Roy, Lauren Gutstein, Karen Huang, Jinhua Wu, Julia Glade Bender, Nicoletta Brega, Arthur M. Buchberg, Vadim Bernard-Gauthier, David S. Hong, Alexander Drilon, Theodore W. Laetsch · 2026
Read NTRK Gene Fusions: A Compendium of Fusion Partners and Tumor Types by Soo-Ryum Yang, Matteo Repetto, Erin R. Rudzinski, Marilyn M. Li, Angshumoy Roy, Lauren Gutstein, Karen Huang, Jinhua Wu, Julia Glade Bender, Nicoletta Brega, Arthur M. Buchberg, Vadim Bernard-Gauthier, David S. Hong, Alexander Drilon, Theodore W. Laetsch (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13155222.txt.
Description
Soo-Ryum Yang and co-authors catalog gene fusions that drive cancers in a 2026 survey. The fusions join a growth gene family to a vast range of partners, and drugs that block the fused protein work across tumor types, so naming the exact partner matters.
Searches of papers, trial records, and two large gene databases yielded hundreds of fusion and tumor pairings across twenty five tumor types. Brain tumors held the most distinct fusions, with soft tissue tumors next. More than two hundred partners appear in total. One pairing shows up in the most tumor types. The catalog aids labs picking the right test.
Catalog record
| CREATOR | Soo-Ryum Yang, Matteo Repetto, Erin R. Rudzinski, Marilyn M. Li, Angshumoy Roy, Lauren Gutstein, Karen Huang, Jinhua Wu, Julia Glade Bender, Nicoletta Brega, Arthur M. Buchberg, Vadim Bernard-Gauthier, David S. Hong, Alexander Drilon, Theodore W. Laetsch |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 28 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |