Fructose Diet–Induced Liver Injury Through Oxidative Stress: A Systematic Review of Preclinical Studies

Marissa Arifin, Wardatul Jannah, Neily Zakiyah, Anna Meiliana, Melisa Intan Barliana, Keri Lestari, Eric Gumpricht · 2026

Read Fructose Diet–Induced Liver Injury Through Oxidative Stress: A Systematic Review of Preclinical Studies by Marissa Arifin, Wardatul Jannah, Neily Zakiyah, Anna Meiliana, Melisa Intan Barliana, Keri Lestari, Eric Gumpricht (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13150434.txt.

Description

Arifin and colleagues review animal studies on how a fruit sugar heavy diet harms the liver in twenty twenty-six. Fructose, the sugar in many sweet drinks and foods, has flooded modern diets. In the liver, too much of it sparks oxidative stress, a flood of damaging oxygen based molecules. The team searched three databases for lab studies from twenty nineteen to twenty twenty-four.

Twenty-six studies met their rules, most with murky reporting of bias. Even low sugar doses over two to three months raised damage markers and cut defenses. A few studies showed defenses rising first, as if the liver tried to adapt. Longer exposure wore defenses down and left lasting injury and fat build up.

Catalog record

CREATORMarissa Arifin, Wardatul Jannah, Neily Zakiyah, Anna Meiliana, Melisa Intan Barliana, Keri Lestari, Eric Gumpricht
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE58 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13150434

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