Transformer-Based Multiomics Study Identifies Important Role of Glycine, Serine, and Threonine Metabolism Pathway in Rheumatoid Arthritis Complicated by Anemia
Jiaxin Huang, Yuanli Wei, Dongmei Wang, Zhuming Yin, Jianghua Chen, Congcong Jian, Xiaoting Zhu, Shilin Li, Jie Zhang, Tingting Wang, Caizhen Liu, Lingli Wei, Jing Gao, Jing Zhu, Qinghua Zou, Jianhong Wu, Fanxin Zeng · 2026
Read Transformer-Based Multiomics Study Identifies Important Role of Glycine, Serine, and Threonine Metabolism Pathway in Rheumatoid Arthritis Complicated by Anemia by Jiaxin Huang, Yuanli Wei, Dongmei Wang, Zhuming Yin, Jianghua Chen, Congcong Jian, Xiaoting Zhu, Shilin Li, Jie Zhang, Tingting Wang, Caizhen Liu, Lingli Wei, Jing Gao, Jing Zhu, Qinghua Zou, Jianhong Wu, Fanxin Zeng (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13150071.txt.
Description
Jiaxin Huang and co-authors hunt for molecular signs of anemia in rheumatoid arthritis using many data types at once, in this 2026 paper. Anemia often joins the joint disease and worsens its course. Its blood markers track closely with inflammation levels.
The team built a cohort with gene, microbe, and chemical profiles from patients and controls. A transformer-based model and several other learners voted on the strongest signals. One pathway, covering glycine, serine, and threonine processing, stood out as central. The marker panel included drained chemicals and raised genes, offering leads for diagnosis and treatment of the combined condition.
Catalog record
| CREATOR | Jiaxin Huang, Yuanli Wei, Dongmei Wang, Zhuming Yin, Jianghua Chen, Congcong Jian, Xiaoting Zhu, Shilin Li, Jie Zhang, Tingting Wang, Caizhen Liu, Lingli Wei, Jing Gao, Jing Zhu, Qinghua Zou, Jianhong Wu, Fanxin Zeng |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 50 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |