Serum CCL1 discriminates infectious and sterile systemic inflammation in sepsis and acute pancreatitis

Marlies Vornhülz, Jennifer Müller, Lara Louisa Takken, Patrick Layritz, Carolin Perleberg, Jan Gärtig, Antonia Beimert, Patrick Weber, Stefan Endres, Julia Mayerle, Lesca Holdt, Ignazio Piseddu, David Anz · 2026

Read Serum CCL1 discriminates infectious and sterile systemic inflammation in sepsis and acute pancreatitis by Marlies Vornhülz, Jennifer Müller, Lara Louisa Takken, Patrick Layritz, Carolin Perleberg, Jan Gärtig, Antonia Beimert, Patrick Weber, Stefan Endres, Julia Mayerle, Lesca Holdt, Ignazio Piseddu, David Anz (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13149532.txt.

Description

Marlies Vornhülz and co-authors test a blood signal in 2026 that may tell infection-driven inflammation from sterile inflammation. Sepsis and pancreas inflammation can look alike, yet only one needs antibiotics fast. The signal they study draws in regulatory immune cells, and the team measured it in patients over a week of care.

The study enrolled 159 patients with sepsis, pancreas inflammation, or other hospital care. Standard markers rose and fell as expected in both diseases. The studied signal, though, ran lower in pancreas cases than in sepsis at every time point, while a sister signal did not differ. In sepsis, lower levels also tracked worse organ failure. The authors see a useful sorting marker.

Catalog record

CREATORMarlies Vornhülz, Jennifer Müller, Lara Louisa Takken, Patrick Layritz, Carolin Perleberg, Jan Gärtig, Antonia Beimert, Patrick Weber, Stefan Endres, Julia Mayerle, Lesca Holdt, Ignazio Piseddu, David Anz
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE32 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13149532

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