KDM3A catalyses the oxidation of acetyl-lysine to hydroxyacetyl-lysine on histone H3K9

Roman Belle, John-Paul Bukowski, Rachel Schiller, Ronald Cutler, Eidarus Salah, Robert S Dawber, Anthony Tumber, Joanna Bonnici, Jessica D Kindrick, Loane Serrano, Patrick Rabe, Catrine Johansson, Marie-Hélène Ruchaud, Richard J Hopkinson, William D Figg, Sr, Paul E Brennan, David R Mole, Simone Sid · 2026

Read KDM3A catalyses the oxidation of acetyl-lysine to hydroxyacetyl-lysine on histone H3K9 by Roman Belle, John-Paul Bukowski, Rachel Schiller, Ronald Cutler, Eidarus Salah, Robert S Dawber, Anthony Tumber, Joanna Bonnici, Jessica D Kindrick, Loane Serrano, Patrick Rabe, Catrine Johansson, Marie-Hélène Ruchaud, Richard J Hopkinson, William D Figg, Sr, Paul E Brennan, David R Mole, Simone Sid (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13149330.txt.

Description

Histone modifications, including Nε-lysine acetylation and methylation, play critical roles in the regulation of eukaryotic transcription. The addition of acetyl and methyl groups and removal of acetyl groups to histones involve redox-neutral reactions. Demethylation is O2-dependent, as reported for reactions catalysed by the 2-oxoglutarate-dependent hypoxia-inducible factor (HIF) hydroxylases, one of which is structurally related to the Jumonji-C (JmjC) histone demethylases.

Catalog record

CREATORRoman Belle, John-Paul Bukowski, Rachel Schiller, Ronald Cutler, Eidarus Salah, Robert S Dawber, Anthony Tumber, Joanna Bonnici, Jessica D Kindrick, Loane Serrano, Patrick Rabe, Catrine Johansson, Marie-Hélène Ruchaud, Richard J Hopkinson, William D Figg, Sr, Paul E Brennan, David R Mole, Simone Sid
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE101 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13149330

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