Primary Hepatoid Adenocarcinoma of the Lung With Signet Ring Cell Differentiation and Widespread Osseous Metastases: A Case Report

Rami Khader, Esraa Elhakim, Mohammad Bdair, Rajaa Abu Sultan, Ameed Khader, Mousa Almasalma, Saleh Ferwana, Mohammed Z. A. Baraka · 2026

Read Primary Hepatoid Adenocarcinoma of the Lung With Signet Ring Cell Differentiation and Widespread Osseous Metastases: A Case Report by Rami Khader, Esraa Elhakim, Mohammad Bdair, Rajaa Abu Sultan, Ameed Khader, Mousa Almasalma, Saleh Ferwana, Mohammed Z. A. Baraka (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13148880.txt.

Description

A rare lung cancer that looks and acts like liver cancer can hide behind a stubborn cough. Rami Khader and co-authors report such a case in 2026: a man in his fifties, a heavy smoker, treated for pneumonia without getting better. Scans later showed a collapsed, consolidated lung lobe, swollen chest glands, and many bone lesions, while the liver itself was clear.

A needle biopsy found a poorly formed gland cancer with signet ring cells, and stains matched the liver-like pattern that names this disease. One usual blood marker stayed normal, which the authors warn does not rule the disease out. Three rounds of chemotherapy failed to slow the decline. They urge early biopsy when lung infection does not resolve.

Catalog record

CREATORRami Khader, Esraa Elhakim, Mohammad Bdair, Rajaa Abu Sultan, Ameed Khader, Mousa Almasalma, Saleh Ferwana, Mohammed Z. A. Baraka
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE20 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13148880

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