NASP functions in the cytoplasm to prevent histone H3 aggregation during early embryogenesis
Mohit Das, Eli Coronado-Chavez, Anusha D Bhatt, Reyhaneh Tirgar, Amanda A Amodeo, Jared T Nordman · 2026
Read NASP functions in the cytoplasm to prevent histone H3 aggregation during early embryogenesis by Mohit Das, Eli Coronado-Chavez, Anusha D Bhatt, Reyhaneh Tirgar, Amanda A Amodeo, Jared T Nordman (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13148224.txt.
Description
Mohit Das and five co-authors show that a histone helper called NASP works in cell soup to stop H3 clump in early fruit fly young. Their study appeared in twenty twenty-six. Helpers haul histones from birth to DNA pack and keep them firm. NASP binds H3 and is key to stop its loss, but where it acts was vague.
In young with low NASP, H3 marks in the core fell, but core in-out rates did not shift head-on. Soup NASP stopped H3 clump in live young. Clump and loss proved two split steps in growth. The team says the chief job of NASP is clump block, which in turn shields H3 from loss.
Catalog record
| CREATOR | Mohit Das, Eli Coronado-Chavez, Anusha D Bhatt, Reyhaneh Tirgar, Amanda A Amodeo, Jared T Nordman |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 60 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |